Division of Nutrition & Dietetics, School of Health Sciences. International Medical University, 57000 Bukit Jalil, Kuala Lumpur.
ABSTRACT
BACKGROUND: Prevalence of hyperphosphatemia is high amongst haemodialysis patients and this is attributed to heavy phosphate binder burden, lack of compliance to dietary phosphate intake as well as phosphate binder regime.
OBJECTIVE: To investigate the association between dietary phosphate intake, binder adherence and the association with hyperphospatemia in haemodialysis patients.
METHODS: This cross-sectional study was conducted amongst 109 haemodialysis patients within Klang Valley. A non-self-administered questionnaire concerning demographics, biochemical data and medical history were used to obtain patient’s background information. The questionnaire also featured a medication chart to gather information on dosage of phosphate binders consumed and prescribed. Morisky Medical Adherence Scale (MMAS-8) was used to measure compliance to phosphate binder and dietary phosphate intake was determined using diet history.
RESULTS: The median daily dietary phosphate intake is 469mg and mainly comes from cereals (28%), seafood (25%) and meat (24.7%). Only 20% of patients were compliant to phosphate binder with median pill intake being 6. Besides that, 91% of patients were overprescribed with phosphate binders, 3% were under prescribed and only 6% were given correct prescriptions. There was no significant association between compliance to phosphate binder regime with compliance to recommended dietary intake (p=0.860).
CONCLUSION: There is no significant association between dietary phosphate intake, binder adherence and the association with hyperphosphatemia. This indicates that not a single factor but many factors contribute to hyperphosphatemia.
Keywords- phosphate, haemodialysis, hyperphosphatemia
No. of words = 240 words excluding title, author’s name, affiliation & keywords